propantheline

What is the most important information I should know about propantheline?

What is propantheline?

Propantheline is used as part of a treatment for a peptic ulcer.

Propantheline may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking propantheline?

• a stomach or bowel obstruction (including paralytic ileus);
• glaucoma;
• a bladder obstruction or other urination problems;
• severe constipation;
• severe ulcerative colitis or toxic megacolon;
• active bleeding with fast heartbeats, low blood pressure, shortness of breath, and cold hands or feet; or
• myasthenia gravis.

Tell your doctor if you have ever had:

• a nerve-muscle disorder;
• heart disease, or a heart rhythm disorder;
• high blood pressure;
• an intestinal disorder such as ulcerative colitis;
• liver or kidney disease;
• hiatal hernia or reflux esophagitis (GERD);
• a thyroid disorder; or
• a colostomy or ileostomy.

Tell your doctor if you are pregnant or breast-feeding.

Older adults may be more sensitive to the effects of this medicine.

How should I take propantheline?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Propantheline is usually taken 3 or 4 times a day, 30 minutes before meals and at bedtime. Follow your doctor's instructions.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Overdose symptoms may include feeling restless or excited, warmth or tingling under your skin, confusion, unusual thoughts or behavior, muscle weakness, or paralysis.

What should I avoid while taking propantheline?

What are the possible side effects of propantheline?

• diarrhea;
• fast or pounding heartbeats, fluttering in your chest;
• eye pain or redness, seeing halos around lights;
• painful or difficult urination; or
• little or no urination.

Common side effects may include:

• dry mouth, nose, or throat;
• blurred vision;
• constipation;
• headache, dizziness, drowsiness;
• confusion or feeling nervous;
• decreased sweating;
• nausea, vomiting, bloating;
• decreased sense of taste;
• impotence, sexual problems; or
• sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect propantheline?

Propantheline slows the digestive tract, which can make it harder for your body to absorb any medicines you take by mouth. Tell your doctor if any of your oral medications do not seem to work as well while you are using propantheline.

Tell your doctor about all your current medicines. Many drugs can affect propantheline, especially:

• heart rhythm medication;
• medicine to treat depression, anxiety, mood disorders, or mental illness;
• cold or allergy medicine (Benadryl and others);
• medicine to treat Parkinson's disease;
• steroid medicine;
• medicine to treat stomach problems, motion sickness, or irritable bowel syndrome;
• medicine to treat overactive bladder; or
• bronchodilator asthma medication.

This list is not complete and many other drugs may affect propantheline. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about propantheline.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 8.01. Revision date: 2/5/2019.