carbidopa and levodopa
Pronunciation: KAR bi DOE pa and LEE voe DOE pa
Brand: Rytary, Sinemet, Sinemet CR
Sinemet
25 mg-100 mg, round, yellow, imprinted with 650
Sinemet CR
50 mg-200 mg, oval, purple, imprinted with 521
Carbidopa-Levodopa
10 mg-100 mg, round, blue, imprinted with 538, R
Carbidopa-Levodopa
25 mg-100 mg, round, yellow, imprinted with 539, R
Carbidopa-Levodopa
25 mg-250 mg, round, blue, imprinted with 540, R
Carbidopa-Levodopa
10 mg-100 mg, round, blue, imprinted with M CL1
Carbidopa-Levodopa
25 mg-100 mg, round, yellow, imprinted with M CL2
Carbidopa-Levodopa CR
25 mg-100 mg, oval, purple, imprinted with 88, MYLAN
Carbidopa-Levodopa CR
50 mg-200 mg, oval, lavender, imprinted with MYLAN, 9 4
Carbidopa-Levodopa
25 mg-250 mg, round, blue, imprinted with M CL3
Carbidopa-Levodopa
10 mg-100 mg, round, green, imprinted with M C51
Carbidopa-Levodopa
25 mg-100 mg, round, blue, imprinted with M C52
Carbidopa-Levodopa
25 mg-250 mg, round, green, imprinted with M C53
Carbidopa-Levodopa ER
25 mg-100 mg, oval, orange, imprinted with L100
Carbidopa-Levodopa CR
50 mg-200 mg, oval, orange, imprinted with L200
Carbidopa-Levodopa
10 mg-100 mg, round, blue, imprinted with R, 538
Carbidopa-Levodopa
25 mg-250 mg, oval, blue, imprinted with 519
Rytary
23.75 mg-95 mg, capsule, blue/white, imprinted with IPX066, 95
Rytary
36.25 mg-145 mg, capsule, blue/light blue, imprinted with IPX066, 145
Rytary
48.75 mg-195 mg, capsule, blue/yellow, imprinted with IPX066, 195
Rytary
61.25 mg-245 mg, capsule, blue, imprinted with IPX066, 245
Carbidopa-Levodopa
25 mg-100 mg, round, yellow, imprinted with TV, 9702
Carbidopa-Levodopa
10 mg-100 mg, round, blue, imprinted with TV, 9701
Carbidopa-Levodopa
10 mg-100 mg, round, blue, imprinted with 93 292
Carbidopa-Levodopa
10 mg-100 mg, round, blue, imprinted with APO, 10 100
Carbidopa-Levodopa CR
25 mg-100 mg, round, brown, imprinted with APO 131
Carbidopa-Levodopa
25 mg-100 mg, round, yellow, imprinted with 93 293, TEVA
Carbidopa-Levodopa
25 mg-250 mg, round, blue, imprinted with 93 294
Carbidopa-Levodopa
25 mg-100 mg, round, yellow, imprinted with APO, 25 100
Carbidopa-Levodopa
25 mg-100 mg, elliptical, yellow, imprinted with Endo 605
Carbidopa-Levodopa CR
25 mg-100 mg, oval, lavender, imprinted with MYLAN, 88
Carbidopa-Levodopa
25 mg-250 mg, round, blue, imprinted with APO, 25 250
Carbidopa-Levodopa
25 mg-250 mg, elliptical, blue, imprinted with Endo 607
Carbidopa-Levodopa
25 mg-100 mg, round, yellow, imprinted with TV, 9702
Carbidopa-Levodopa CR
50 mg-200 mg, round, tan, imprinted with APO 132
Carbidopa-Levodopa CR
50 mg-200 mg, oval, lavender, imprinted with MYLAN, 9 4
Carbidopa-Levodopa CR
50 mg-200 mg, oval, orange, imprinted with ETH, 383
Carbidopa-Levodopa CR
25 mg-100 mg, oval, purple, imprinted with 392, G
Carbidopa-Levodopa CR
50 mg-200 mg, oval, purple, imprinted with 391, G
Carbidopa-Levodopa
10 mg-100 mg, round, blue, imprinted with m 711
Carbidopa-Levodopa
25 mg-100 mg, round, yellow, imprinted with m 721
Carbidopa-Levodopa
25 mg-250 mg, round, blue, imprinted with m 731
Parcopa
10 mg-100 mg, round, blue, mint, imprinted with 10/100, SP 341
Parcopa
25 mg-100 mg, round, yellow, mint, imprinted with 25/100, SP 342
Parcopa
25 mg-250 mg, round, blue, mint, imprinted with 25/250, SP 343
Sinemet
10 mg-100 mg, round, blue, imprinted with 647
Sinemet
10 mg-100 mg, oval, blue, imprinted with 647, SINEMET
Sinemet
25 mg-100 mg, round, yellow, imprinted with 650
Sinemet
25 mg-250 mg, round, blue, imprinted with 654
Sinemet
25 mg-250 mg, elliptical, blue, imprinted with SINEMET, 654
Sinemet CR
25 mg-100 mg, oval, purple, imprinted with 601
Sinemet CR
25 mg-100 mg, elliptical, pink, imprinted with SINEMET CR, 601
Sinemet CR
50 mg-200 mg, elliptical, peach, imprinted with SINEMET CR, 521
Sinemet CR
50 mg-200 mg, oval, purple, imprinted with 521
Carbidopa-Levodopa
25 mg-100 mg
Carbidopa-Levodopa
25 mg-250 mg
What is the most important information I should know about carbidopa and levodopa?
Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.
What is carbidopa and levodopa?
Carbidopa and levodopa is a combination medicine used to treat symptoms of Parkinson's disease, such as stiffness or tremors.
Carbidopa and levodopa is also used to treat Parkinson symptoms caused by carbon monoxide poisoning or manganese intoxication.
Carbidopa and levodopa may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking carbidopa and levodopa?
You should not use this medicine if you are allergic to carbidopa or levodopa, or if you have:
- narrow-angle glaucoma.
Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.
Tell your doctor if you have ever had:
- heart disease, high blood pressure, or heart attack;
- liver or kidney disease;
- an endocrine (hormonal) disorder;
- asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;
- a stomach or intestinal ulcer;
- open-angle glaucoma; or
- depression, mental illness, or psychosis.
The disintegrating tablet may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).
People with Parkinson's disease may have a higher risk of skin cancer (melanoma). Talk to your doctor about this risk and what skin symptoms to watch for.
Tell your doctor if you are pregnant or breastfeeding.
How should I take carbidopa and levodopa?
If you already take levodopa, you must stop taking it at least 12 hours before you start taking carbidopa and levodopa.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take this medicine at regular intervals, with or without food.
Swallow the capsule whole and do not crush, chew, break, or open it.
The tablet is sometimes broken in half to give the correct dose. Always swallow a whole or half tablet without chewing or crushing.
Place the orally disintegrating tablet in your mouth and allow it to dissolve, without chewing.
It may take up to several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Tell your doctor if the effects of this medicine wear off quickly between doses.
If you use this medicine long-term, you may need frequent medical tests.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using carbidopa and levodopa.
Do not stop using carbidopa and levodopa suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Get your prescription refilled before you run out of medicine completely.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking carbidopa and levodopa?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Avoid taking iron supplements or eating a diet high in protein. These things can make it harder for your body to digest and absorb carbidopa and levodopa. Talk with your doctor or dietitian about the best foods to eat or avoid.
What are the possible side effects of carbidopa and levodopa?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
- worsening of tremors (uncontrolled shaking);
- severe or ongoing vomiting or diarrhea;
- confusion, hallucinations, unusual changes in mood or behavior;
- depression or suicidal thoughts; or
- severe nervous system reaction --very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.
Some people taking carbidopa and levodopa have fallen asleep during normal daytime activities such as working, talking, eating, or driving. Tell your doctor if you have any problems with daytime sleepiness or drowsiness.
You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.
You may notice that your sweat, urine, or saliva appears dark in color, such as red, brown, or black. This is not a harmful side effect, but it may cause staining of your clothes or bed sheets.
Common side effects may include:
- jerky or twisting muscle movements;
- headache, dizziness;
- low blood pressure (feeling light-headed);
- sleep problems, strange dreams;
- dry mouth;
- muscle contractions; or
- nausea, vomiting, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect carbidopa and levodopa?
Other drugs may affect carbidopa and levodopa, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information?
Your pharmacist can provide more information about carbidopa and levodopa.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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