epirubicin

What is the most important information I should know about epirubicin?

Tell your caregivers if you feel any burning, pain, or swelling around the needle when epirubicin is injected.

Epirubicin affects your immune system. You may get infections more easily, even serious or fatal infections. You will need frequent medical tests and your cancer treatments may be delayed.

What is epirubicin?

Epirubicin is used to treat breast cancer.

Epirubicin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before I receive epirubicin?

• an untreated or uncontrolled infection (including mouth sores);
• severe liver disease;
• severe heart problems; or
• if you have recently had a heart attack.

You may not be able to use epirubicin if you have already been treated with a certain amount of other cancer medications.

Tell your doctor if you have ever had:

• heart problems;
• radiation to your chest area;
• liver or kidney disease;
• bone marrow suppression; or
• chemotherapy with doxorubicin, daunorubicin, epirubicin, idarubicin, or mitoxantrone.

Using epirubicin may increase your risk of developing other cancers, such as leukemia. Ask your doctor about this risk.

Epirubicin may cause you to stop having menstrual periods and may also cause premature menopause. Talk with your doctor if you have concerns about these risks.

How is epirubicin given?

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using epirubicin.

Epirubicin is given as an infusion into a vein. A healthcare provider will give you this injection.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when epirubicin is injected.

Epirubicin affects your immune system. You may get infections more easily, even serious or fatal infections. Your blood will need to be tested often. Your heart function may also need to be checked using an electrocardiograph or ECG (sometimes called an EKG). Your cancer treatments may be delayed based on the results of these tests.

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while receiving epirubicin?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of epirubicin?

• fast or slow heartbeats;
• easy bruising, unusual bleeding, purple or red spots under your skin;
• unusual tiredness, feeling light-headed or short of breath, cold hands and feet;
• pain, blistering, redness, bruising, or skin changes where the injection was given;
• severe vomiting;
• dehydration symptoms --feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
• fluid build-up in or around the lungs --pain when you breathe, feeling short of breath while lying down, wheezing, gasping for breath, cough with foamy mucus, cold and clammy skin, anxiety, rapid heartbeats;
• signs of tumor cell breakdown --tiredness, weakness, muscle cramps, nausea, vomiting, diarrhea, fast or slow heart rate, tingling in your hands and feet or around your mouth; or
• signs of infection --fever, chills, flu symptoms, mouth sores, shallow breathing, pale or blue-colored skin.

Common side effects may include:

• nausea, vomiting, diarrhea;
• temporary hair loss;
• blisters or ulcers in your mouth, red or swollen gums, trouble swallowing;
• hot flashes, missed menstrual periods;
• discoloration of your skin or nails;
• lack of energy; or
• red-colored urine for 1 or 2 days after each injection.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect epirubicin?

Tell your doctor about all your other medicines, especially:

• cimetidine (Tagamet);
• other cancer medicines; or
• heart or blood pressure medication.

This list is not complete. Other drugs may affect epirubicin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your doctor or pharmacist can provide more information about epirubicin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 6.02. Revision date: 3/13/2020.