paclitaxel protein-bound

What is the most important information I should know about paclitaxel protein-bound?

What is paclitaxel protein-bound?

Paclitaxel protein-bound is used to treat advanced cancer of the breast, lung, or pancreas. This medicine is used when the cancer cannot be treated with surgery or after other treatments have failed.

Paclitaxel protein-bound is sometimes given with other cancer medicines.

Paclitaxel protein-bound may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving paclitaxel protein-bound?

• a low white blood cell count; or
• severe liver disease.

Tell your doctor if you have ever had:

• liver disease;
• kidney disease; or
• an allergic reaction to medicines like paclitaxel protein-bound (such as cabazitaxel or docetaxel).

• If you are a woman, do not use paclitaxel protein-bound if you are pregnant. You may need to have a negative pregnancy test before starting this treatment. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
• If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.
• Tell your doctor right away if a pregnancy occurs while either the mother or the father is using paclitaxel protein-bound.

This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because paclitaxel protein-bound can harm an unborn baby.

Paclitaxel protein-bound is made from donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.

How is paclitaxel protein-bound given?

Paclitaxel protein-bound is given as an infusion into a vein. A healthcare provider will give you this injection.

For breast cancer, this medicine is usually given once every 3 weeks.

For cancer of the lung or pancreas, this medicine is given in a 21-day or 28-day treatment cycle. You will receive this medicine only on certain days of each cycle.

Your doctor will determine how long to treat you with this medicine.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when paclitaxel protein-bound is injected.

You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results.

What happens if I miss a dose?

What happens if I overdose?

What should I avoid while using paclitaxel protein-bound?

What are the possible side effects of paclitaxel protein-bound?

• numbness, tingling, pain, or weakness in your hands or feet;
• sudden chest pain or discomfort, rapid heart rate;
• dry cough, shortness of breath, rapid and shallow breathing;
• easy bruising, unusual bleeding, purple or red spots under your skin;
• low white blood cell counts --fever, mouth sores, skin sores, sore throat, cough, trouble breathing;
• low red blood cells (anemia) --pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet;
• dehydration symptoms --headache, muscle pain, thirst, dry mouth, hot and dry skin, vomiting, diarrhea, dark urine, being unable to urinate; or
• a blood infection (sepsis) --fever, flu symptoms, mouth and throat ulcers, rapid heart rate, shallow breathing.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

• fever, chills, or other signs of infection;
• bruising, bleeding, anemia;
• numbness, tingling, or swelling in your hands or feet;
• hair loss, rash;
• nausea, vomiting, diarrhea, loss of appetite;
• irregular heartbeats;
• feeling tired;
• muscle and joint pain;
• abnormal liver function tests; or
• dehydration.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect paclitaxel protein-bound?

Other drugs may affect paclitaxel protein-bound, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your doctor or pharmacist can provide more information about paclitaxel protein-bound.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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