gadoxetate

What is the most important information I should know about gadoxetate?

What is gadoxetate?

Gadoxetate is a contrast agent that has magnetic properties. It is used in combination with magnetic resonance imaging (MRI) to allow blood vessels, organs, and other non-bony tissues to be seen more clearly.

Gadoxetate is used to help diagnose certain disorders of the liver.

Gadoxetate may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before receiving gadoxetate?

Gadoxetate can stay in your body for months or years after you receive this medicine. It is not known whether this could cause any health problems in people whose kidneys work properly. Tell your doctor if you have had repeated scans with a contrast agent, and provide the date of your last scan.

Tell your doctor if you have ever had:

• kidney problems;
• any type of reaction to a contrast agent;
• diabetes;
• high blood pressure;
• liver disease;
• asthma, hay fever, food or drug allergies;
• an injury, surgery, or severe infection; or
• if you are over 60 years old.

How is gadoxetate given?

Gadoxetate is given as an infusion into a vein. A healthcare provider will give you this injection.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when gadoxetate is injected.

Gadoxetate can affect the results of certain medical tests for at least 24 hours after your MRI. Tell any doctor who treats you that you have received gadoxetate

What happens if I miss a dose?

Since gadoxetate is used only during your MRI, you will not be on a dosing schedule.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving gadoxetate?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of gadoxetate?

Some side effects of gadoxetate may occur up to several days after injection.

• burning, itching, swelling, scaling, and tightening or hardening of your skin;
• tiredness, muscle weakness;
• joint stiffness in your arms, hands, legs, or feet;
• deep bone pain in your ribs or your hips;
• trouble moving; or
• skin redness or dark patches.

• kidney problems --little or no urinating, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
• swelling, irritation, or skin changes where the injection was given.

Common side effects may include:

• headache, back pain;
• dizziness;
• nausea; or
• feeling hot.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect gadoxetate?

Other drugs may affect gadoxetate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your doctor or pharmacist can provide more information about gadoxetate.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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