nebivolol and valsartan

What is the most important information I should know about nebivolol and valsartan?

What is nebivolol and valsartan?

Nebivolol and valsartan is a combination medicine used in adults to treat high blood pressure (hypertension).

Nebivolol and valsartan may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking nebivolol and valsartan?

• a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker);
• severe heart failure (that required you to be in the hospital or take certain medicines);
• very low heartbeats (severe bradycardia); or
• severe liver disease.

If you have diabetes, do not use nebivolol and valsartan with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking nebivolol and valsartan with aliskiren if you have kidney disease.

Tell your doctor if you have or have ever had:

• low blood pressure;
• heart problems;
• asthma or lung disease;
• diabetes;
• thyroid disorder;
• blood flow problems to your feet and legs (peripheral vascular disease);
• pheochromocytoma (tumor of the adrenal gland);
• a severe allergic reaction to any blood pressure medication;
• if you are on a low-salt diet;
• if you plan to have surgery with general anesthesia;
• liver disease; or
• kidney disease (or if you are on dialysis).

How should I take nebivolol and valsartan?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take nebivolol and valsartan with or without food.

Your blood pressure will need to be checked often. Your potassium levels and kidney function may also need to be checked.

If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Overdose symptoms may include heart failure, dizziness, low blood sugar, tiredness, vomiting, slow or fast heartbeats, or fainting.

What should I avoid while taking nebivolol and valsartan?

What are the possible side effects of nebivolol and valsartan?

• feeling like you might pass out;
• very slow heartbeats;
• low blood sugar --headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;
• heart attack symptoms --chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
• heart problems --swelling, rapid weight gain, feeling short of breath;
• kidney problems --swelling, urinating less, feeling tired or short of breath; or
• high blood potassium --nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects may include:

• slow heartbeats.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect nebivolol and valsartan?

Tell your doctor about all your current medicines. Many drugs can affect nebivolol and valsartan, especially:

• cyclosporine;
• fluoxetine;
• lithium;
• rifampin;
• ritonavir;
• a diuretic or "water pill";
• other heart or blood pressure medicines; or
• NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete and many other drugs may affect nebivolol and valsartan. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your doctor or pharmacist can provide more information about nebivolol and valsartan.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2023 Cerner Multum, Inc. Version: 5.01. Revision date: 6/30/2023.