mitapivat
What is the most important information I should know about mitapivat?
Call your doctor at once if you have jaundice (yellowing of the skin or eyes), dark urine, dizziness, confusion, tiredness, or shortness of breath.
What is mitapivat?
Mitapivat is used to treat low red blood cell counts caused by hemolytic anemia (early breakdown of red blood cells) in adults with pyruvate kinase deficiency.
Mitapivat may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before taking mitapivat?
Tell your doctor if you have ever had:
- liver disease.
Tell your doctor if you are pregnant or breastfeeding.
How should I take mitapivat?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take mitapivat with or without food.
Swallow the tablet whole and do not crush, chew, or break it.
Do not share this medicine with another person, even if they have the same symptoms you have.
Do not change your dose or stop using mitapivat without talking to your doctor. Your doctor will give you instructions for stopping mitapivat.
Store this medicine in the original container at room temperature.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if you are more than 4 hours late for the dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking mitapivat?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What are the possible side effects of mitapivat?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- jaundice (yellowing of the skin or eyes);
- dark urine;
- dizziness;
- confusion;
- tiredness; or
- shortness of breath.
Common side effects may include:
- flushing (sudden warmth, redness, or tingly feeling);
- breast swelling and tenderness;
- changes in sexual function;
- irregular heart rhythm;
- abnormal blood tests; or
- back or joint pain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect mitapivat?
Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.
Other drugs may affect mitapivat, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Where can I get more information?
Your doctor or pharmacist can provide more information about mitapivat.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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