teclistamab
What is the most important information I should know about teclistamab?
Tell your medical caregivers if you have symptoms of a serious side effect, such as fever, chills, trouble breathing, vomiting, or severe tiredness.
Call your doctor if you have symptoms of neurological problems such as headache, jerking muscle movements, numbness and tingling, tremor, double vision, problems walking, hearing loss.
What is teclistamab?
Teclistamab is used to treat adults with multiple myeloma who have received at least 4 treatment regimens and their cancer has returned or did not respond to a previous treatment.
Teclistamab is available only from a certified pharmacy under a special program.
Teclistamab may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before receiving teclistamab?
Tell your doctor if you have:
- an infection.
You may need to have a negative pregnancy test before starting this treatment.
May harm an unborn baby. Use effective birth control while using teclistamab and for at least 5 months after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using this medicine, and for at least 5 months after your last dose.
How is teclistamab given?
Follow all directions on your prescription label and read all medication guides or instruction sheets.
Read the Patient Wallet Card about serious side effects and learn what symptoms to watch for. Keep the card with you at all times.
Teclistamab is given by a healthcare provider as an injection under the skin in the stomach-area, thigh, or another area.
You will need to stay in the hospital for 48 hours after some doses of teclistamab. Talk with your doctor if you have any questions.
You may be given other medications to help prevent serious side effects. Keep taking these medicines for as long as your doctor has prescribed.
Your treatment with teclistamab may be temporarily or completely discontinued if you have certain side effects.
You will need medical tests before and during treatment with teclistamab.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your teclistamab injection.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while receiving teclistamab?
Avoid driving or hazardous activity for 48 hours after receiving certain doses of this medicine or until neurological symptoms go away. Your reactions could be impaired.
What are the possible side effects of teclistamab?
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.
Call your doctor at once if you have:
- bruising, swelling, warmth, redness, oozing, or bleeding where an injection was given;
- low white blood cell counts --fever, mouth sores, skin sores, sore throat, cough;
- neurological problems --headache, jerking muscle movements, rigid muscles, feeling restless, numbness and tingling, confusion, problems speaking, muscle spasms, tremors, double vision, changes in handwriting, problems walking, muscle weakness in body or face, hearing loss, burning, throbbing, or stabbing pain;
- signs of infection --fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding; or
- liver problems --loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects may include:
- headache;
- nausea, diarrhea;
- tiredness, weakness;
- joint pain, muscle pain in the back, chest, arms, and legs;
- cold symptoms such as stuffy nose, sneezing, sore throat; or
- fever, chills, cough with mucus, chest pain, feeling short of breath.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect teclistamab?
Other drugs may affect teclistamab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Where can I get more information?
Your doctor or pharmacist can provide more information about teclistamab.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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