This medicine is used for the following purposes:
- arthritis
- autoimmune disorder
- inflammatory disease
- psoriasis
- cancer
Brand Name(s): Trexall
Generic Name: Methotrexate
Instructions
This medicine may be taken with or without food.
Keep the medicine at room temperature. Avoid heat and direct light.
Drink extra water while on this medicine. Adults should try to drink 6-8 cups (48 to 64 oz.) of water every day.
This medicine can make you sensitive to the sun. Use sunscreen or protective clothing when in sun.
It may take several weeks for this medicine to fully work.
It is important that you keep taking each dose of this medicine on time even if you are feeling well.
If you miss a dose, contact your doctor for instructions.
Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.
Tell your doctor if symptoms do not get better or if they get worse.
Talk to your doctor before taking other medicines, including aspirins and ibuprofen containing products. Speak to your doctor about which medicines are safe to use while you are on this medicine.
Keep all appointments for medical exams and tests while on this medicine.
Cautions
Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.
Some patients on this medicine have developed severe, life-threatening infections. Please speak with your doctor about the risks and benefits of using this medicine.
This medicine is associated with a rare, but serious problem of the liver. Speak to your doctor about the early signs of liver problems and the benefits and risks of using this medicine.
There is an increased risk of bleeding while on this medicine, please tell your doctor or nurse if you notice any excessive bleeding or bruising.
Do not use the medication any more than instructed.
Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.
Please check with your doctor before drinking alcohol while on this medicine.
This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.
Speak with your health care provider before receiving any vaccinations.
Do not breastfeed while on this medicine. You may safely start breastfeeding 1 week after stopping treatment.
Do not use this medicine if you are pregnant. If you become pregnant, contact your doctor immediately.
Women must use reliable forms of birth control while taking this medicine and for 6 months after stopping to prevent pregnancy.
Men should continue using birth control for at least 3 months after finishing this medicine.
Do not share this medicine with anyone who has not been prescribed this medicine.
Side Effects
The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.
- dizziness or drowsiness
- lack of energy and tiredness
- hair loss
- mouth sores or irritation
- nausea and vomiting
- red, burning, or itchy skin
- stomach upset or abdominal pain
- blurring or changes of vision
Call your doctor or get medical help right away if you notice any of these more serious side effects:
- back pain
- bleeding or bruising
- bone pain
- cough that does not go away
- diarrhea
- fever or chills
- severe or persistent headache
- fast or irregular heart beats
- signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
- mood changes
- muscle pain or weakness
- pale or blue skin, lips or fingernails
- seizures
- shortness of breath
- bloody or dark, tarry stools
- urinating less often
- blood in urine
- severe or persistent vomiting
- weakness on one side of the body
A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.
Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.
IMPORTANT NOTE: This document tells you briefly how to take your medicine, but it does not tell you all there is to know about it. Your doctor or pharmacist may give you other documents about your medicine. Please talk to them if you have any questions. Always follow their advice.
There is a more complete description of this medicine available in English. Scan this code on your smartphone or tablet or use the web address below. You can also ask your pharmacist for a printout. If you have any questions, please ask your pharmacist.
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More information about METHOTREXATE - ORAL
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Conditions of Use: The information in this database is intended to supplement, not substitute for the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express Terms of Use.
