Romidepsin Injection (ROMIDEPSIN - INJECTION)

For treating cancer.

Generic Name: Romidepsin

Instructions

This is an IV medicine. It is given through a sterile tube directly into the vein by a healthcare provider.

This medicine should be given over 4 hours.

This medicine should be given by a trained health care provider.

Drink plenty of water while on this medicine.

Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Your doctor may prescribe other medications to reduce side effects. Follow instructions carefully.

This medicine can make birth control pills work less well. Ask your doctor or pharmacist how long you should use an extra form of birth control, such as condoms.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Do not breastfeed while on this medicine. You may safely start breastfeeding 1 week after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women of childbearing age should have a negative pregnancy test before starting this medicine.

To prevent pregnancy, men and women must use reliable forms of birth control while taking this medicine and for 1 month after stopping it.

Do not take St. John's wort while on this medicine.

Always carry an ID card or wear a medical alert bracelet indicating your medical condition.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • decreased appetite
  • lack of energy and tiredness
  • nausea and vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • back pain
  • bleeding or bruising
  • chest pain
  • cough that does not go away
  • fainting
  • fever or chills
  • fast or irregular heart beats
  • signs of kidney damage (such as change in urine color or bubbly urine)
  • muscle cramps or weakness
  • pale or blue skin, lips or fingernails
  • unusual or unexplained tiredness or weakness
  • difficulty or discomfort urinating

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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