Venlafaxine
Drug Information
Venlafaxine is a drug used to treat depression. It is unrelated to other drugs used to treat depression.
Common brand names:
Effexor, Effexor XRSummary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
none
Reduce Side Effects
none
Support Medicine
none
Reduces Effectiveness
none
Potential Negative Interaction
There is one published report of a woman collapsing after taking venlafaxine in combination with the Chinese herbal remedy sour date nut (Ziziphus jujube), although she tolerated venlafaxine by itself without side effects. People taking venlafaxine should not take sour date nut.
- 5-HTP
Venlafaxine, a potent serotonin reuptake inhibitor, has been associated with several cases of serotonin syndrome. 5-HTP and L-tryptophan are converted to serotonin in the brain, and taking them with venlafaxine may increase venlafaxine-induced side effects. While no interactions with venlafaxine and 5-HTP or L-tryptophan have been reported, until more is known, people taking venlafaxine are cautioned to avoid 5-HTP or L-tryptophan.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence. - L-Tryptophan
Venlafaxine, a potent serotonin reuptake inhibitor, has been associated with several cases of serotonin syndrome. 5-HTP and L-tryptophan are converted to serotonin in the brain, and taking them with venlafaxine may increase venlafaxine-induced side effects. While no interactions with venlafaxine and 5-HTP or L-tryptophan have been reported, until more is known, people taking venlafaxine are cautioned to avoid 5-HTP or L-tryptophan.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence. - St. John’s Wort
Although there have been no interactions reported in the medical literature, it is best to avoid using venlafaxine with St. John’s wort unless you are under the supervision of a qualified healthcare professional.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Explanation Required
none
Last Review: 03-18-2015
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